Listar Investigación por autor "Ugarte, Ana"
Mostrando ítems 1-3 de 3
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Concomitant histone deacetylase and phosphodiesterase 5 inhibition synergistically prevents the disruption in synaptic plasticity and it reverses cognitive impairment in a mouse model of Alzheimer's disease
Cuadrado-Tejedor, Mar; García-Barroso, Carolina; Sánzhez-Arias, Juan Antonio; Mederos, Sara; Rabal, Obdulia; [et al.] (2015)article -
Design, synthesis and biological evaluation of novel matrix metalloproteinase inhibitors as potent antihemorrhagic agents: from hit identification to an optimized lead
Orbe, Josune; Sánchez-Arias, Juan Antonio; Rabal, Obdulia; Rodríguez, Jose Antonio; Salicio, Agustina; [et al.] (2015)article -
Discovery and safety profiling of a potent preclinical candidate, (4-[4-[[(3R)-3-(hydroxycarbamoyl)-8-azaspiro[4.5]decan-3-yl]sulfonyl]phenoxy]-N-methylbenzamide) (CM-352), for the prevention and treatment of hemorrhage
Orbe, Josune; Rodríguez, Jose Antonio; Sánchez-Arias, Juan Antonio; Salicio, Agustina; Belzunce, Miriam; [et al.] (2105)article