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Pilot study of feasibility and dosimetric comparison of prone versus supine breast radiotherapy
dc.contributor.author | E. Ferna´ndez-Lizarbe A. Montero (&) A. Polo R. Hernanz R. Morı´s A. Ramos | |
dc.date.accessioned | 2024-01-18T08:55:33Z | |
dc.date.available | 2024-01-18T08:55:33Z | |
dc.date.issued | 2013 | |
dc.identifier.citation | Clin Transl Oncol . 2013 Jun;15(6):450-9. doi: 10.1007/s12094-012-0950-8. Epub 2012 Nov 10. | es |
dc.identifier.uri | http://hdl.handle.net/20.500.12020/1043 | |
dc.description.abstract | Purpose: The aim of this study was to demonstrate feasibility and analyze dosimetric differences in prone and supine position breast cancer radiotherapy in women with large or pendulous breast. Methods: Ten post-lumpectomy breast cancer patients underwent supine and prone computed tomography-based treatment plan. On each data set, the whole breast, the ipsilateral lung and the heart were outlined. Multisegment tangential-fields plans were generated for each position. Target coverage, homogeneity, overdosage outside breast and organ at risk sparing were analyzed and compared for supine and prone position. Results: Coverage and dose homogeneity of the PTV measured by D 90 and V(95)% were similar for both plans although breast maximum dose was higher in the supine plan (p = 0.017). Prone position reduced the percentage of ipsilateral lung receiving 20 Gy (V(20Gy)) from 26.5 to 2.9 % (p = 0.007), medium lung dose, as well as the percentage of the heart receiving 35 Gy heart (V(35Gy)) from 3.4 to 1.2 % (p = 0.038). Overdosage of areas outside breast PTV was also consistently reduced with prone position (p = 0.012). In addition, average number of segments and monitor units needed was reduced in prone position. Conclusions: Prone position in large breast women appears to favor normal tissue sparing in breast radiotherapy as compared to supine position, without diminishing the target coverage. | es |
dc.language.iso | en | es |
dc.title | Pilot study of feasibility and dosimetric comparison of prone versus supine breast radiotherapy | es |
dc.type | article | es |
dc.identifier.doi | 10.1007/s12094-012-0950-8 | |
dc.journal.title | Clinical and Translational Oncology | es |
dc.page.initial | 450 | es |
dc.page.final | 459 | es |
dc.rights.accessRights | openAccess | es |
dc.subject.area | Ciencias Biomédicas | es |