TY  - JOUR 
AU  - Cuadrado-Tejedor, Mar
AU  - Garcia-Barroso, Carolina
AU  - Sánchez-Arias, Juan Antonio
AU  - Rabal, Obdulia
AU  - Pérez-González, Marta
AU  - Mederos, Sara
AU  - Ugarte, Ana
AU  - Franco, Rafael
AU  - Segura, Victor
AU  - Perea, Gertrudis
AU  - Oyarzabal, Julen
AU  - Garcia-Osta, Ana
PY  - 2016
SN  - 0893-133X
UR  - http://hdl.handle.net/20.500.12020/1551
AB  - The targeting of two independent but synergistic enzymatic activities, histone deacetylases (HDACs, class I and HDAC6) and phosphodiesterase 5 (PDE5), has recently been validated as a potentially novel therapeutic approach for Alzheimer's disease...
LA  - en
PB  - Springer Nature [academic journals on nature.com] American College of Neuropsychopharmacology (ACNP)
TI  - A First-in-Class Small-Molecule that Acts as a Dual Inhibitor of HDAC and PDE5 and that Rescues Hippocampal Synaptic Impairment in Alzheimer's Disease Mice
DO  - https://doi.org/10.1038/npp.2016.163
T2  - Neuropsychopharmacology
M2  - 524
KW  - Dual Inhibitor
KW  - Alzheimer’s Disease
KW  - Tg2576
VL  - 42
ER  -