In Vitro Activities of Amphotericin B, Caspofungin, Itraconazole, Posaconazole, and Voriconazole against 45 Clinical Isolates of Zygomycetes: Comparison of CLSI M38-A, Sensititre YeastOne, and the Etest

Identifiers
URI: http://hdl.handle.net/20.500.12020/1283
ISSN: 0066-4804
DOI: 10.1128/AAC.01539-06
Author/s
Torres-Narbona, Marta; Guinea, Jesús; Martinez-Alarcon, Jose; Pelaez, Teresa; Bouza, Emilio
Date
2007-03-01
Document type
article
Área/s de conocimiento
Ciencias Biomédicas
Materia/s Unesco
3201.03 Microbiología Clínica
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Abstract
We evaluated the activities of amphotericin B, itraconazole, voriconazole, caspofungin, and posaconazole against zygomycetes by CLSI M38-A, Etest and Sensititre. The most active drug was posaconazole, followed by amphotericin B and itraconazole. The correlation of the Etest and Sensititre with CLSI M38-A was moderate for posaconazole but poor for the others.
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