TY  - JOUR 
AU  - Orbe, Josune
AU  - Sánchez-Arias, Juan Antonio
AU  - Rabal, Obdulia
AU  - Rodríguez, Jose Antonio
AU  - Salicio, Agustina
AU  - Ugarte, Ana
AU  - Belzunce, Miriam
AU  - Musheng, Xu
AU  - Wei, Wu
AU  - haizhong, Tan
AU  - hongyu, Ma
AU  - Páramo, Jose Antonio
AU  - Oyarzabal, Julen
PY  - 2015
SN  - 0022-2623
UR  - http://hdl.handle.net/20.500.12020/1199
AB  - Growing evidence suggests that matrix metalloproteinases (MMP) are involved in thrombus dissolution; then, considering that new therapeutic strategies are required for controlling hemorrhage, we hypothesized that MMP inhibition may reduce bleeding by...
LA  - en
PB  - American Chemical Society
TI  - Design, synthesis and biological evaluation of novel matrix metalloproteinase inhibitors as potent antihemorrhagic agents: from hit identification to an optimized lead
DO  - https://doi.org/10.1021/jm501940y
T2  - Journal of Medicinal Chemistry
M2  - 2465
KW  - metalloproteinase
KW  - inhibitors
KW  - antihemorrhagic
VL  - 58
ER  -