TY  - JOUR 
AU  - Garrofé-Ochoa, Xènia
AU  - Melero Fernandez de Mera, Raquel Maria
AU  - Fernandez Gomez, Francisco Jose
AU  - Ribas, Judit
AU  - Jordan, Joaquin
AU  - Boix, Jacint
PY  - 2008
SN  - 1538-8514
UR  - http://hdl.handle.net/20.500.12020/1186
AB  - In previous reports, we have shown in SH-SY5 cells that olomoucine and roscovitine, two inhibitory drugs of cyclin-dependent kinases, caused apoptosis independent of the extrinsic pathway. In this experimental paradigm, apoptosis was refractory to the...
LA  - en
PB  - American Association for Cancer Research
TI  - BAX and BAK proteins are required for cyclin-dependent kinase inhibitory drugs to cause apoptosis
DO  - 10.1158/1535-7163.MCT-08-0655
T2  - Molecular Cancer Therapeutics
M2  - 3800
KW  - BAX
KW  - BAK
KW  - Proteins
KW  - Mitochondrial permeability
KW  - Caspase
KW  - Cyclin dependent kinase
KW  - Cytochrome C
KW  - Apoptosis
KW  - Enzyme activation
VL  - 7
ER  -