TY  - JOUR 
AU  - Cuadrado-Tejedor, Mar
AU  - García-Barroso, Carolina
AU  - Sánzhez-Arias, Juan Antonio
AU  - Mederos, Sara
AU  - Rabal, Obdulia
AU  - Ugarte, Ana
AU  - Franco, Rafael
AU  - Pascual-Lucas, Maria
AU  - Segura, Victor
AU  - Perea, Gertrudis
AU  - Oyarzabal, Julen
AU  - García-Osta, Ana
PY  - 2015
SN  - 1868-7083
UR  - http://hdl.handle.net/20.500.12020/1178
AB  - Background: Given the implication of histone acetylation in memory processes, histone deacetylase inhibitors (HDACIs) have been postulated as potential modulators of cognitive impairment in Alzheimer's disease (AD). However, dose-dependent side...
LA  - en
PB  - BMC
TI  - Concomitant histone deacetylase and phosphodiesterase 5 inhibition synergistically prevents the disruption in synaptic plasticity and it reverses cognitive impairment in a mouse model of Alzheimer's disease
DO  - https://doi.org/10.1186/s13148-015-0142-9
T2  - Clinical Epigenetics
M2  - 108
KW  - Alzheimer’s disease
KW  - Amyloid
KW  - Gene transcription
KW  - Histone deacetylase
KW  - Memory
KW  - Phosphodiesterase
KW  - Tau
VL  - 7
ER  -