TY - JOUR AU - Gómez-Lazaro, María AU - Galindo, María Francisca AU - Melero Fernández de Mera, Raquel María AU - Fernández Gómez, Francisco José AU - Cancannon, CG AU - Segura, Miguel AU - Comella, Joan X AU - Prehn, J H M AU - Jordan, Joaquin PY - 2007 SN - 15210111 UR - http://hdl.handle.net/20.500.12020/1157 AB - Malonate, an inhibitor of mitochondrial complex II, is a widely used toxin to study neurodegeneration in Huntington's disease and ischemic stroke. We have shown previously that malonate increased reactive oxygen species (ROS) production in human... LA - en PB - American Society for Pharmacology and Experimental Therapeutics TI - Reactive oxygen species and p38 mitogen-activated protein kinase activate Bax to induce mitochondrial cytochrome c release and apoptosis in response to malonate DO - https://doi.org/10.1124/mol.106.030718 T2 - Molecular Pharmacology M2 - 1 KW - Animals KW - Cells, Cultured KW - Protein Transport / drug effects KW - Reactive Oxygen Species KW - Malonates / pharmacology VL - 71 ER -