TY - JOUR AU - Sufan, Roxana I AU - Moriyama, Eduardo H AU - Mariampillai, Adrian AU - Roche, Olga AU - Evans, Andrew J AU - Alajez, Nehad M AU - Vitkin, I Alex AU - Yang, Victor X D AU - Liu, Fei-Fei AU - Wilson, Brian C AU - Ohh, Michael PY - 2009 SN - 1757-4676 UR - http://hdl.handle.net/20.500.12020/1150 AB - Tumour hypoxia promotes the accumulation of the otherwise oxygen-labile hypoxia-inducible factor (HIF)-a subunit whose expression is associated with cancer progression, poor prognosis and resistance to conventional radiation and chemotherapy. The... LA - en PB - EMBO Press TI - Oxygen-independent degradation of HIF-alpha via bioengineered VHL tumour suppressor complex DO - https://doi.org/10.1002/emmm.200900004 T2 - EMBO Molecular Medicine M2 - 66 KW - ARNT KW - HIF KW - VHL KW - Cancer Renal KW - Von Hippel Lindau VL - 1 ER -